The 44-year-old shared an replace on her battle with most cancers on a July 23 episode of her Two T’s in a Pod podcast.

“Basically, I have not been feeling good for a couple of month, which was sort of surprising to me and I believe mentally did rather a lot to me,” Mellencamp shared. “I used to be like, what do you imply? I felt so good after the surgical procedures.”

Mellencamp was first recognized with stage two melanoma in 2022 after she seen an irregular spot on her again.

Since then, she’s undergone a number of surgical procedures to take away the spots over the previous two years. In February 2025, Mellencamp was recognized with a number of mind tumors that she had eliminated and in March 2025 shared she now had tumors in her lungs.

Shortly after, the tumors in her mind returned, however she shared optimistic progress in April 2025.

Nevertheless, Mellencamp’s struggles did not cease there. Now, she shares her problem together with her immunotherapy remedies.

“After I was having radiation and immune remedy, I used to be feeling good so why am I not ready to do that proper now? Like, why do I really feel like I can barely open my eyes or preserve my phrases straight?” she questioned.

“And I sort of realized why this week on the physician’s.”

“I would been having some thyroid points, so that they put me on some medicine for that,” the fact star defined.

“So I do know that Matt and Eric mentioned slightly bit about one thing about immunotherapy, the way it can have an effect on your wholesome cells and typically issues change.”

She went on to share that in the first place she felt nice post-treatments and had the vitality to lastly do every single day duties.

“Basically, what we discovered with me was, sure, I began out feeling nice, and I might do all of the pods and I might do all this stuff,” she mentioned.

“I might go to all my daughter’s horse exhibits and I might keep at my home on my own, and I felt actually robust.”

And though Mellencamp understood that immunotherapy helps together with her most cancers, she’s simply shied away from sharing the way it’s additionally been slowing her down.

“What’s taking place with me is the longer that I am on immunotherapy, the sicker it is making me.”

“So for some individuals, particularly after they come from, you already know, having mind tumors eliminated, radiation, immunotherapy, all of this stuff directly, that is after they really feel their worst,” she famous.

“And I really feel like even my associates which are nurses or docs have been like, what the heck’s occurring with Teddi?”

In consequence, she revealed that her docs had helped her come to the choice to pause the remedies for now, “as a result of this immune remedy has hit me so extremely exhausting.”

The purpose is to get her “physique again feeling stronger,” Mellencamp defined. “And I’m on steroids and we’re doing every little thing that we are able to to get me again to feeling like I, you already know, I can do that, I can do all of the issues.”