Applegate, utilizing a cane and leaning on a good-looking escort, acquired a standing ovation and went on so as to add a couple of extra hilarious quips together with a dig at Ozempic

As she walked out on stage to current the Excellent Supporting Actress in a Comedy Sequence award to Ayo Edebiri for her position in The Bear, to the theme music of Married With Kids — the tv present which made her a family title — her fellow friends gave her a standing ovation.

“You are completely shaming me and my incapacity by standing up,” Applegate, who has a number of sclerosis, joked earlier than including, “Physique not by Ozempic.”

Twitter was quickly full of viewers noting how inspirational Applegate is.

Simply final yr, in an interview with The Los Angeles Occasions in August 2023, the actress revealed she’s not taking up any performing initiatives and mentioned the upcoming Display Actors Guild Awards will “most likely” be the final time attending an awards present as an actor.

In August 2021, “The Sweetest Factor” star revealed she had been recognized with MS and has been very open about her expertise with the illness in interviews main as much as the discharge of the third season of “Useless to Me,” which hit Netflix in November 2022. Applegate acquired her MS analysis throughout manufacturing.

Throughout her interview with the LA Occasions, Applegate mirrored on her expertise engaged on the ultimate season of “Useless to Me,” praising the solid and crew, together with her co-star Linda Cardellini, whom she known as “an unimaginable human.”

Whereas she typically struggled because of her sickness, the “Trip” star mentioned everybody on set was there to help her.

“I used to be a wreck day by day, however most of that wreck would happen in my trailer on my own,” Applegate recalled. “However there have been occasions I might break down on set and be like, ‘I can not, now we have to take a break, I want a half-hour,’ and everybody was so loving that it was OK.’”